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A glass of red wine before the 'chemo'?

Source:
Maria Valerio - The Mundo.es

have long researchers know the amazing anti-aging properties of resveratrol, a compound present in the skin of red grapes and, consequently, in the wine. Now, a laboratory experiment suggests that this potent antioxidant may be the perfect addition to antitumor treatment: rapamycin.

Rapamycin used in the treatment of some tumors such as breast, but to the frustration of oncologists, it is not surprising that cancer cells acquire the ability to 'escape' with their work and emerging resistance. In an experimental investigation
published in 'Cancer Letters' , just check that the use of resveratrol pretreatment significantly inhibited the growth of malignant cells
. The assay was performed with tumor cell lines of breast cancer in the laboratory, which is soon to transfer the results to patients in the flesh. However, their comments in hand, the team of Charis Eng (Institute of Genomic Medicine of Cleveland, USA) dares to suggest "a diet rich in resveratrol during treatment with rapamycin-like drugs." That would not be surprising that a few years to recommend some grapes or a glass of wine before getting the 'chemo'. cells in his laboratory, and Eng colleagues found that adding the antioxidant to rapamycin could reduce tumor cell growth by 50%. But also have explored the mechanism that could explain this synergy so beneficial.

The key may be in two oncogenes, such as PTEN and AKT, which seem 'off' somehow in the presence of resveratrol. Thus, the antioxidant
reduces
resistance mechanisms represent both elements in the presence of rapamycin (an immunosuppressant that is also used as a treatment to prevent rejection after organ transplantation).

Given that even today, despite all the advances made in the fight against breast cancer, many tumors are able to generate resistance, the researchers stress the need for "new drugs or drug combinations to replace or complement the currently existing."